1982 ACR Criteria for Diagnosis of Systemic Lupus Erythematosus

malar rash

fixed erythema, flat or raised, over the malar eminences

discoid rash

erythematous raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occur

photosensitivity

oral ulcers

includes oral and nasopharyngeal. observed by physician

arthritis

nonerosive arthritis involving 2 or more peripheral joints, characterized by tenderness, swelling or effusion

serositis

pleuritis or pericarditis, or evidence of pericardial effusion

renal disorder

proteinuria (> 0.5 g/d, or > 3+) or cellular casts

neurologic disorder

seizures without other cause or psychosis without other cause

hematologic disorder

hemolytic anemia, leukopenia (< 4,000 per µL), lymphopenia (< 1,500 per µL) or thrombocytopenia (< 100,000 per µL), in the absence of a causative drug

immunologic disorder

positive LE cell preparation, anti-ds DNA antibody, anti-Sm antibodies, false positive VDRL

antinuclear antibodies

abnormal ANA titer at any point of time in the absence of drugs known to induce ANA