Description

A cancer patient with febrile neutropenia is evaluated after the first 3 to 5 days of empiric therapy. If the patient is afebrile then further therapy can be adjusted or discontinued. The authors are from the Infectious Diseases Society of America (IDSA) and multiple hospitals in the North America and Europe.


 

Patient selection: afebrile after first 3 to 5 days of therapy

 

Parameters:

(1) etiology of infection identified

(2) initial risk status

(3) age of the patient

 

Etiology

Initial Risk Status

Age of the Patient

Management

unknown

low

adult

ciprofloxacin and amoxicillin/

clavulanate

unknown

low

pediatric

cefixime

unknown

high

NA

continue previous regimen

identified

NA

NA

optimize regimen for agent

 

A patient who is low risk and afebrile can be discharged on oral medications in most cases.

 


To read more or access our algorithms and calculators, please log in or register.