Gordon et al reported the 3-factor risk estimate scale (TRES) to quantify comorbidity in an adult with non-Hodgkin's lymphoma. The authors are from the University of Texas MD Anderson Cancer Center and City of Hope National Medical Center.
Categories:
(1) vascular
(2) upper gastrointestinal
(3) endocrinal
Conditions under vascular:
(1) venous insufficiency
(2) lymphedema
(3) carotid stenosis
(4) deep vein thrombosis or pulmonary embolus
(5) atherosclerosis (leg claudication, angina, TIA)
(6) history of surgical or endovascular intervention for atherosclerosis
(7) antiplatelet agent therapy
(8) aortic stenosis
Conditions under upper GI:
(1) proton pump inhibitor use
(2) documented peptic ulcer disease or history of perforated ulcer
(3) acute or chronic pancreatitis
(4) melena
(5) prior upper GI cancer
Conditions under endocrinal:
(1) diabetes treated with oral agent or insulin
(2) hyperthyroidism
(3) obesity
(4) adrenal insufficiency
(5) thyroid, breast, or adrenal malignancy
|
Parameter
|
Finding
|
Points
|
|
vascular conditions
|
0
|
0
|
|
|
>= 1
|
1
|
|
upper GI conditions
|
0
|
0
|
|
|
>= 1
|
1
|
|
endocrine conditions
|
0
|
0
|
|
|
>= 1
|
1
|
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
|
TRES
|
Risk Category
|
3-Year Cumulative Mortality Rate
|
|
0
|
low
|
7%
|
|
1
|
intermediate
|
12%
|
|
2 or 3
|
high
|
18%
|
