Kanchanasurakit et al reported the ABCDF-S score to identify the risk of a patient developing hyponatremia while being treated with hydrochlorothiazide. This can help to identify a patient who should be monitored for this complication. The authors are from Phayao University, Phrae Hospital, and Phisanulok University in Thailand.
ABCDF-S is an acronym for age, benzodiazepine, CVA, dose, female, and statin.
Parameters:
(1) age of the patient in years
(2) benzodiazepine therapy
(3) history of cerebrovascular accident
(4) dose of hydrochlorothiazide in mg per day
(5) sex
(6) statin therapy
Parameter
Finding
Points
age of the patient
< 65 years
0
>= 65 years
2
benzodiazepine therapy
no
0
yes
1
cerebrovascular accident
no
0
yes
3.5
dose per day
< 25 mg
0
>= 25 mg
5
sex
male
0
female
2
statin therapy
no
0
yes
-2
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: -2
• maximum score: 13.5
Score
Risk Category
-2 to 5.9
low
6.0 to 7.9
moderate
>= 8.0
high
Performance:
• The area under the ROC curve is 0.81.
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