Adhoute et al reported the ABCR score as a guide for managing a patient with hepatocellular carcinoma. The authors are from multiple institutions in France.
TACE = transarterial chemoembolization
Patient selection: intermediate stage hepatocellular carcinoma after first TACE
Parameters after first TACE:
(1) A: serum AFP concentration in ng/mL
(2) B: Barcelona Clinic Liver Cancer (BCLC) stage (A, B, C)
(3) C: increase in Child-Pugh score (range for Child-Pugh score 5 to 15)
(4) R: tumor response on imaging studies
Parameter
Finding
Point
serum AFP concentration
< 200 ng/mL
0
>= 200 ng/mL
1
BCLC stage
A
0
B
2
C
3
Child-Pugh increase
no increase
0
+1
0
>= 2
2
tumor response
no
0
yes
-3
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: -3
• maximum score: 6
• A score >= 4 indicates a patient who is unlikely to benefit from a second TACE procedure.
Total Score
Median Overall Survival
<= 0
34.5 months
1, 2, or 3
13.2 months
>= 4
4.6 months
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