Algorithm of Wilson and Burns for Diagnosis of a Focal Liver Mass Using Microbubble Contrast-Enhanced Pulse-Inversion Sonography

Description

Wilson and Burns used microbubble contrast-enhanced pulse-inversion sonography to characterize focal hepatic masses. These can help to distinguish benign from malignant lesions. The authors are from the University of Toronto.

Patient selection: presence of a focal mass in the liver

Method: microbubble contrast-enhanced pulse-inversion sonography

Parameters:

(1) sustained enhancement in extended portal phase

(2) arterial intensity (predominant pattern)

(3) arterial pattern

(4) progression over time

Extended Portal Phase	Arterial Intensity	Arterial Pattern	Progression over Time	Diagnosis
>= liver	< liver	peripheral nodular and/or pools and puddles	centripetal progression	hemangioma
>= liver	> liver	diffuse	NA	focal nodular hyperplasia
>= liver	NA	NA	NA	probably benign
< liver	> liver	diffuse	NA	hepatocellular carcinoma
< liver	< liver	sparse or rim	NA	malignancy, not HCC
< liver	NA	NA	NA	probably malignant

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Algorithm of Wilson and Burns for Diagnosis of a Focal Liver Mass Using Microbubble Contrast-Enhanced Pulse-Inversion Sonography

Description

Specialty