Alopecia and changes to the hair are relatively common in patients with lupus erythematosus. Identifying the cause is important for developing a treatment strategy. Onset of hair changes prior to diagnosis of lupus erythematosus can be a diagnostic challenge.
Changes that may occur:
(1) hair loss (alopecia)
(2) changes in texture
Hair loss may range from minor to total.
Lupus-Related Alopecia |
Comment |
telogen effluvium |
severe systemic disease with marked physiologic stress or may be drug-induced |
cicatricial (scarring) alopecia |
aggressive therapy prior to scarring may reverse hair loss and allow regrowth |
alopecia areata |
rare |
drug-induced |
may improve with change in dose or change in drug selection |
patchy non-scarring |
cannot be assigned to one of the other groups above; treatment of lupus can allow hair regrowth |
"Lupus hair" is the most common change in hair quality. Features of "lupus hair":
(1) short and stubby frontal hair
(2) irregular lengths
(3) imparts a disheveled appearance
Other changes to the scalp in a patient with lupus may include:
(1) photosensitivity
(2) erythema, plaque or other cutaneous lesions
(3) chilblains
(4) vasculitis
Hair loss unrelated to lupus:
(1) androgenetic alopecia in a woman
(2) other drugs
(3) infection
Purpose: To evaluate changes to the hair in a patient with lupus erythematosus.
Specialty: Immunology/Rheumatology
Objective: severity, prognosis, stage, differential diagnosis and mimics, red flags, disease progression, prevention
ICD-10: L65.9, M32,