The Absolute Monocyte and Lymphocyte Prognostic Index (AMPLI) can help to stratify patients with diffuse large B-cell lymphoma. This can help to identify a patient who may benefit from more aggressive management. The authors are from Roswell Park Cancer Center and M.D. Anderson Cancer Center.
Patient selection: diffuse large B-cell lymphoma treated with R-CHOP
Parameters at presentation:
(1) absolute lymphocyte count (ALC)
(2) absolute monocyte count (AMC)
ALC
AMC
Risk
> 1,000 per µL
< 610 per µL
low
<= 1,000 per µL
< 610 per µL
intermediate
> 1,000 per µL
>= 610 per µL
intermediate
<= 1,000 per µL
>= 610 per µL
high
The AMPLI can help to stratify patients with an IPI from 0 to 2.
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