Hereditary nephrogenic diabetes insipidus (DI) is a rare condition that can be a challenge to manage in the perioperative period.
Concerns:
(1) dehydration, especially if made NPO (nil per ora)
(2) handling the urine output, especially if urinary retention develops
Hydration:
(1) Use of normal saline (0.9% NaCl) can result in hypernatremia.
(2) The patient should receive his or her normal oral intake of water as 2.5% dextrose in water (D2.5W)
(3) Drug therapy to reduce polyuria such thiazide with (amiloride or indomethacin).
(4) Carefully monitoring fluid balance, recording input and output.
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Specialty: Anesthesiology, Pedatrics, Genetics
