Description

A few Bacillus species other than B. anthracis may harbor virulence genes and cause a clinical syndrome similar to anthrax.


Implicates species:

(1) B. cereus

(2) B. tropicus

 

These species have one or more virulence genes shared with B. anthracis.

(1) cytK (cytoxin K)

(2) sph (sphingomyelinase)

(3) pi-plc (phosphatidylinositol phospholipase)

(4) nheABC gene complex (nonhemolytic enterotoxin)

(5) entFM (enterotoxin FM)

(6) hblCDA gene complex (hemolysin BL)

 

pXO1 is a plasmid that encodes anthrax toxin and other virulence factors.

 

Testing can be performed through a laboratory in the state's Laboratory Response Network.

 

Infections caused by anthrax-like bacteria include:

(1) skin

(2) pneumonia

(3) gastrointestinal

(4) sepsis

 

A patient infected with one of these species should receive anthrax antitoxin in addition to antibiotics. Raxibacumab is a monoclonal antibody approved for inhalation anthrax.


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