The American Society of Clinical Oncology (ASCO) has reviewed complications associated with immune checkpoint inhibitor therapy.
Patient selection: myositis following therapy with an immune checkpoint inhibitor
Parameters:
(1) weakness
(2) activities of daily living (ADL)
|
Weakness
|
Activities of Daily Living
|
Grade
|
|
mild with or without pain
|
usual
|
G1
|
|
moderate with or without pain
|
limits instrumental ADL
|
G2
|
|
severe with or without pain
|
limits self-care ADL
|
G3/G4
|
The diagnosis requires exclusion of other causes of weakness and disability.
The presence of concomitant myocarditis and/or myasthenia is associated with a worse prognosis.
