BAAT Score for Septal Fibrosis in Overweight Patient

 

Patient selection: overweight with body mass index > 25 kg per square meter for at least 5 years with unexplained abnormal liver function tests

 

Outcome: septal fibrosis on liver biopsy

 

Parameters:

(1) body mass index (BMI)

(2) age in years

(3) serum ALT in IU/L

(4) serum triglyceride concentration in mmol/L

 

Parameter	Finding	Points
BMI	< 28 kg per sq meter	0
	>= 28 kg per square meter	1
age	< 50 years	0
	>= 50 years of age	1
serum ALT	< 2 times the upper limit of normal (ULN)	0
	>= 2 times ULN	1
serum triglycerides	< 1.7 mmol/L	0
	>= 1.7 mmol/L	1

 

BAAT score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 4

• The higher the score the greater the risk of septal fibrosis.

 

Performance:

• The prevalence of septal fibrosis in the study population was 30%.

• With a cutoff score of >= 2, the sensitivity was 0.71 and specificity 0.80.

• With a cutoff score of >= 3, the sensitivity was 0.14 but the specificity 1.0.