Dilsen et al listed criteria for interpreting the results of the skin pathergy test (SPT) in a patient with suspected Behcet’s disease. The authors are from the University of Istanbul in Turkey.
Synonym: nonspecific skin hyperreactivity, needle prick test
Method for the skin pathergy test (SBT):
(1) An intradermal prick is made with a sterile blunt needle.
(2) The site is examined at 48 hours for the presence of erythema, papule and/or pustule.
where:
• The authors noted that the intensity of the test results was better when a blunt needle was used compared to a sharp needle.
• Some authors inject normal saline intradermally rather than make a needle prick.
Interpretation:
• A positive skin test reading at 48 hours is specific for Behcet’s Disease.
Skin Change |
Diameter |
Interpretation |
erythema or scratch |
NA |
negative |
papule and erythema |
papule < 2 mm |
suspect |
papule and erythema |
papule 2 to 3 mm |
1+ |
papule and erythema |
papule > 3 mm |
2+ |
pustule |
pustule 1-2 mm |
3+ |
pustule |
pustule > 2 mm |
4+ |
Purpose: To evaluate a pathergy skin test in a patient suspected of having Behcet's disease based on the criteria of Dilsen et al.
Specialty: Immunology/Rheumatology
Objective: criteria for diagnosis
ICD-10: M35.2,