Description

Shireman et al developed a model for predicting the risk of bleeding for an elderly patient being treated with warfarin. This can help identify a patient who may benefit from closer monitoring during anticoagulant therapy. The authors are from the University of Kansas and University of Iowa.


Patient selection: patients with atrial fibrillation, typically > 65 years of age

 

Parameters:

(1) age of the patient in years

(2) gender

(3) history of remote bleeding

(4) history of recent bleeding

(5) alcohol and/or drug abuse

(6) diabetes mellitus

(7) anemia

(8) therapy with an antiplatelet agent

 

Parameter

Finding

Points

age of the patient

< 70 years of age

0

 

>= 70 years of age

1

gender

male

0

 

female

1

history of remote bleeding

absent

0

 

present

1

history of recent bleeding

absent

0

 

present

1

alcohol and/or drug abuse

absent

0

 

present

1

diabetes mellitus

absent

0

 

present

1

anemia

absent

0

 

present

1

antiplatelet agent therapy

absent

0

 

present

1

 

risk score =

= (0.49 * (points for age of the patient)) + (0.32 * (points for gender)) + (0.58 * (points for remote bleeding)) + (0.62 * (points for recent bleeding)) + (0.71 * (points for alcohol or drug abuse)) + (0.27 * (points for diabetes)) + (0.86 * (points for anemia)) + (0.32 * (points for antiplatelet agent therapy))

 

Interpretation:

• minimum score: 0

• maximum score: 4.17

• The higher the score the greater the risk of bleeding.

 

Risk Score

Risk of Bleeding

<= 1.07

low

1.08 to 2.18

moderate

>= 2.19

high

 


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