Description

Boric acid (H3BO3, boron with 3 hydroxy units) is used as a preservative for urine specimens.


 

Action: bacteriostatic when present at 10 to 20 g/L. It can be bactericidal at high concentrations.

 

Indications:

(1) time between collection and testing is > 2 hours

(2) to stabilize the specimen for microbiological studies

 

Available as: dry chemical

 

Amount to add to urine: 10 to 15 grams for a 24 hour urine (or 10 to 20 g/L)

 

Specimens preserved with boric acid can be cultured for bacteria and yeast.

 

Specimens preserved with boric acid are suitable for the following chemical analyses:

(1) albumin, total protein, microalbumin

(2) aldosteronecalcium

(3) cateacholamines, metanephrines, vanillylmandelic acid (VMA)

(4) chloride

(5) chorionic gonadotropin

(6) citrate

(7) corticosteroids: cortisol, 17-hydroxycorticosteroids (17-OH), 17-ketosteroids

(8) creatine

(9) creatinine

(10) estrogens

(11) FSH or LH

(12) glucose

(13) histamine and methylhistamine

(14) 5-hydroxyindolacetic acid (5-HIAA)

(15) iron

(16) microglobulin

(17) NTX-telopeptide

(18) oxalate

(19) prostaglandins

(20) sulfate

(21) uric acid

 

It is not suitable for specimens being submitted for

(1) heavy metal analysis

(2) dipstick urinalysis

(3) urine cytology

 


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