Description

In 2004 British Isles Lupus Assessment Group (BILAG) revised its index for evaluating disease activity in patients with systemic lupus erythematosus (SLE). This was based on the physician's intent to treat. The authors are from multiple universities in Great Britain.


 

Systems evaluated:

(1) constitutional

(2) mucocutaneous

(3) neuropsychiatric

(4) musculoskeletal

(5) cardiorespiratory

(6) gastrointestinal

(7) renal

(8) hematological

(9) ophthalmic

Disease Activity

Designation

Points

marked activity

A

9

moderate activity

B

3

mild and stable activity

C

1

inactivity

D

0

no activity ever

E

0

 

where:

• Constitutional replaces "general" in the original index.

• Neuropsychiatric replaces "neurological".

• Cardiorespiratory replaces "cardiopulmonary".

• Ophthalmic has been added.

• Gastrointestinal has been added.

• Vascular has been removed.

• System activity has replaced organ involvement.

 

number of components with marked activity =

= SUM(number of components with marked activity)

 

number of components with moderate or marked activity =

= SUM(number of components with marked activity, number of components with moderate activity)

 

total score =

= SUM(points for all 9 components)

 

Interpretation:

• minimum total score: 0

• maximum total score: 72

• minimum number of components with marked activity: 0

• maximum number of components with marked activity: 9

• minimum number of components with moderate or marked activity: 0

• maximum number of components with moderate or marked activity: 9

• The higher the scores the greater the disease activity.

 


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