Description

Mulrow et al measured the burden of disease (BOD) on an elderly patient based on measurement of a list of conditions. This can be used to monitor the impact of disease over time. The authors are from the University of Texas Health Science Center and Audie L. Murphy Memorial Veterans Hospital in San Antonio, Texas.


 

Parameters (59):

valvular heart disease

ischemic heart disease

conduction defects and arrhythmias

cardiac failure

arterial hypertension

hypotension

arterial aneurysm

cerebrovascular disease

peripheral arterial disease (PAD)

thrombophlebitis

chronic lung disease

pulmonary embolism and/or infarct

chronic lung infection, non-bacterial

diabetes mellitus

hyperlipidemia

thyroid disease

dementia

intermittent confusion and/or combativeness

Parkinson’s disease

myelopathy

seizure disorder

cerebellar disorder

hemiparesis, hemiplegia, paraplegia

neuropathy

liver disease

gastrointestinal disease, non-rectal

gastrointestinal disease, rectal (including incontinence)

biliary and/or pancreatic disease

electrolyte disorders

kidney diseases

lower genitourinary disorders (urinary bladder, prostate, urethra)

eye disease

gynecological disorder

sexual dysfunction

arthritis

bone disease, including osteoporosis

nonspecific muscle pain or spasm, fibrositis

chronic pain syndrome

diffuse connective tissue disorder

anemia

malignancy, hematologic

malignancy, solid tumor

malignancy, skin

AIDS

depression

anxiety

psychosis or schizophrenia

sleep disorder

substance abuse, non-alcohol

substance abuse, alcohol

skin disorder, wounds and ulcers

skin disorder, other

infections

injuries

fractures

surgeries

syncope

headache

other

Severity

Points

none

0

inactive

1

mild

2

moderate

3

severe

4

 

total score =

= SUM(points for all 59 items)

 

Interpretation:

• minimum score: 0

• maximum score: 236

• The higher the score the more severe the burden of illness.

 

Limitations:

• The classification of disease is uneven with vastly different diseases weighted equally.

• Some categories (like non-bacterial chronic lung infection) are suboptimal.

• Some disorders are not mentioned or else lumped under non-specific categories.

• Weighting is linear by disease severity but the burden is nonlinear.

• An inactive disease should be no burden to the patient.

 


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