CAP (C-Reactive Protein, Albumin, Platelet Count) Score of Hashimoto et al for a Patient with Hepatocellular Carcinoma

Description

Hashimoto et al developed a simple score for evaluating patients with hepatocellular carcinoma. This is based on preoperative measurement of C-reactive protein, serum albumin and the platelet count. The authors are from Fukuoka City Hospital and Nigata University Medical Hospital in Japan.

Parameters - preoperative measurements of:

(1) C-reactive protein (CRP)

(2) serum albumin level in g/dL

(3) platelet count per µL

Parameter	Finding	Points
C-reactive protein (CRP)	< 1.0 mg/dL (normal)	0
	>= 1.0 mg/dL (increased)	1
serum albumin	>= 4.0 g/dL (normal or increased)	0
	< 4.0 g/dL (decreased)	1
platelet count	>= 120,000 per µL (normal or increased)	0
	< 120,000 per µL (decreased)	1

where:

• The reference range for serum albumin of 4.0 to 5.0 g/dL may differ from levels in the US (lower limit around 3.2 to 3.4 g/dL depending on age).

• The reference range for platelet count of 120,000 to 380,000 per µL may differ from levels in the US (150,000 to 400,000 per µL seems a common range).

total CAP score =

= SUM(points for all 3 parameters)

Interpretation:

• minimum score: 0

• maximum score: 3

• The higher the score the worse the prognosis.

Total Score	Prognostic Group	5 Year Survival	10 Year Survival
0	good	74%	54%
1	fair	57%	33%
2 or 3	poor	27%	6%

from Figure 4, page 1862

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Description

Specialty

ICD-10