Some herbs used as alternative remedies contain potential carcinogens. Linking a tumor to a causative herbal remedy can be difficult.
Criteria for implicating an herb as the cause of a malignancy:
(1) chronic exposure to an herb containing a potential carcinogen, especially if in high doses
(2) diagnosis of a tumor associated with the potential carcinogen
(3) exclusion of other causes for the neoplasm
where:
• The carcinogen may be associated with a named herb, or it may be present as an adulterant or contaminant.
Potential Carcinogen
Possible Source
beta-asarone
Aconus calamus (calamus oil)
aristolochic acids
Aristolochis species
phorbol diesters
Croton tiglium
safrole
Sassafras albidum
pyrrolidizidine alkaloids
Symphtum officinale, other
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Specialty: Pharmacology, clinical