Description

Rychik et al reported a cardiovascular score for fetuses with the twin-twin transfusion syndrome (TTTS). This can help to identify the cardiac abnormalities that may be seen in the recipient fetus. The authors are from Children's Hospital of Philadelphia and University of Pennsylvania.


Patient selection: pregnancy with twin-twin syndrome

 

Analysis: Doppler ultrasonography

 

Parameters:

(1) umbilical artery blood flow in donor fetus

(2) ventricular hypertrophy in recipient fetus

(3) cardiac dilation in recipient fetus

(4) ventricular dysfunction in recipient fetus

(5) tricuspid valve regurgitation (TVR) in recipient fetus

(6) mitral valve regurgitation (MVR) in recipient fetus

(7) tricuspid valve (TV) inflow in recipient fetus

(8) mitral valve (MV) inflow in recipient fetus

(9) ductus venosus blood flow in recipient fetus

(10) umbilical vein pulsations in recipient fetus

(11) right-sided outflow tract in recipient fetus

(12) pulmonary valve regurgitation (PVR) in recipient fetus

 

Parameter

Finding

Points

umbilical artery blood flow in donor

normal

0

 

decreased diastolic

1

 

absent or reversed diastolic blood flow

2

ventricular hypertrophy in recipient

none

0

 

present

1

cardiac dilation in recipient

none

0

 

mild

1

 

moderate or severe

2

ventricular dysfunction in recipient

none

0

 

mild

1

 

moderate or severe

2

TVR in recipient

none

0

 

mild

1

 

moderate or severe

2

MVR in recipient

none

0

 

mild

1

 

moderate or severe

2

TV inflow in recipient

double-peak

0

 

single peak

1

MV inflow in recipient

double-peak

0

 

single peak

1

ductus venosus in recipient

all antegrade

0

 

absent diastolic blood flow

1

 

reverse diastolic blood flow

2

umbilical vein of recipient

no pulsations

0

 

pulsations

1

right-sided outflow tract in recipient

pulmonary artery > aorta

0

 

pulmonary artery = aorta

1

 

pulmonary artery < aorta

2

 

RV outflow obstruction

3

PVR in recipient

none

0

 

present

1

 

total score =

= SUM(points for all 12 parameters)

 

Interpretation:

minimum score: 0

maximum score: 20

 

Total Score

Cardiovascular Grade

0 to 5

1

6 to 10

2

11 to 15

3

16 to 20

4

 


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