Causes Fever Unknown Origin | Medical Algorithm

Are you evaluating a patient with FUO?

Yes

Have you considered?

• bacterial endocarditis?

Yes

• tuberculosis?

Yes

• deep fungal infection?

Yes

• Epstein Barr virus (EBV), CMV, viral hepatitis or other chronic viral infection?

Yes

• chronic bacterial infection (brucellosis, yersiniosis, Campylobacter, Salmonelllosis)?

Yes

• occult abscess (liver, lung, psoas, subphrenic, perirectal, dental, etc)?

Yes

• chronic cholecystitis?

Yes

• malaria?

Yes

• chronic urinary tract infection?

Yes

• osteomyelitis?

Yes

• leptospirosis?

Yes

• necrotizing lymphadenitis?

Yes

• vasculitis (hypersensitivity, giant cell, primary angiitis of the CNS, Wegener's)?

Yes

• polymyalgia rheumatica?

Yes

• Still's disease or adult onset Still's disease?

Yes

• SLE?

Yes

• rheumatoid arthritis?

Yes

• Weber Christian disease?

Yes

• polymyositis?

Yes

• scleroderma?

Yes

• Behcet's disease?

Yes

• Sjogren's syndrome?

Yes

• cryoglobulinemia?

Yes

• malignant non-Hodgkins's lymphoma?

Yes

• Hodgkin's disease?

Yes

• renal cell carcinoma?

Yes

• nasopharyngeal carcinoma?

Yes

• lung cancer?

Yes

• multiple myeloma?

Yes

• leukemia?

Yes

• hepatoma?

Yes

• pancreatic cancer?

Yes

• gastric cancer?

Yes

• adrenocortical carcinoma?

Yes

• Castleman's disease?

Yes

• sarcoma?

Yes

• atrial myxoma?

Yes

• factitious fever?

Yes

• sarcoidosis?

Yes

• Crohn's disease?

Yes

• idiopathic hypereosinophilic syndrome?

Yes

• chronic thyroiditis or hyperthyroidism?

Yes

• postmyocardial infarction syndrome?

Yes

• severe gout?

Yes

• alcoholic hepatitis?

Yes

• Familial Mediterranean fever or other periodic fevers?

Yes

• recurrent thrombophlebitis?

Yes

• Sweet's syndrome?

Yes

• drugs?

Yes

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Specialty

Objective

ICD-10

Conditions Associated with Fever of Unknown Origin (FUO)

Purpose: To evaluate a patient for the various conditions associated with fever of unknown origin (FUO).