Neonatal hepatitis can be caused by a wide range of conditions.
Presentation of neonatal hepatitis: jaundice, pale stools, dark urine, hyperbilirubinemia and elevated serum transaminases
Genetic disorders with neonatal hepatitis:
(1) galactosemia
(2) alpha-1 antitrypsin deficiency
(3) cystic fibrosis
(4) chromosomal abnormality
(5) Niemann-Pick disease
(6) Gaucher's disease
(7) hyperimmunoglobulinemia D syndrome (HIDS)
Infectious causes of neonatal hepatitis
(1) hepatitis A, B or C
(2) toxoplasmosis
(3) bacterial infections
(4) cytomegalovirus (CMV)
(5) scrub typhus
(6) Herpesvirus
(7) other viruses
Other:
(1) hepatotoxin
(2) drug reaction
Differential diagnosis:
(1) hemolytic disease of the newborn
(2) biliary atresia
(3) other cause of obstructive jaundice
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Specialty: Pedatrics, Gastroenterology, Infectious Diseases
