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Chiba HCC in Intermediate Prognostic (CHIP) Score of Ogasawara et al

Description

Ogasawara et al reported a prognostic score for patients with intermediate stage hepatocellular carcinoma (HCC). This can identify a patient who may benefit from more aggressive management. The authors are from Chiba University and Numazu City Hospital in Japan.


Patient selection: intermediate-stage hepatocellular carcinoma (BCLC stage B without macrovascular invasion or extrahepatic metastasis) with Child Pugh Score 5 to 9

 

Parameters:

(1) Child-Pugh score (from 5 to 15)

(2) number of liver tumors

(3) HCV RNA

 

Parameter

Finding

Points

Child-Pugh score

5

0

 

6

1

 

7

2

 

8 or 9

3

number of liver tumors

1

0

 

2 to 7

2

 

>= 8

3

HCV RNA

negative

0

 

positive

1

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 7

• The higher the score the worse the prognosis.

 

Score

Group

Median Survival

0 to 2

1

65.2 months

3

2

29. 2months

4

3

24.3 months

5

4

13.1 months

6 or 7

5

8.4 months

 


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