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Chronic Hepatitis C Outcome Model

Purpose: To evaluate a patient with chronic hepatitis C using the model of Bonis et al.

Description

Bonis et al reported a model for evaluating a patient with chronic hepatitis C (HCV). This can help to identify a patient who may benefit from more aggressive management. The authors are from Yale University, LA County USC School of Medicine, National Genetics Institute (Boulder) and Tufts University.


Patient selection: chronic hepatitis C (HCV)

 

Outcomes: liver failure, hepatocellular carcinoma or liver transplant

 

Parameters:

(1) history of hepatic decompensation (relative risk 4.3)

(2) serum albumin (relative risk 0.253)

 

History of Decompensation

Serum Albumin

Chance of Poor Outcome within 5 Years

no

>= 4.1 g/dL

3.2%

no

< 4.1

 

yes

>= 4.1g/dL

 

yes

< 4.1 g/dL

40%

 


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Specialty

Objective

ICD-10