Clinical findings:
(1) dyspnea
(2) orthopnea
(3) cough
(4) pleural effusion
(5) pleuritic chest pain
(6) hemoptysis
Imaging findings:
(1) pulmonary infiltrate
Laboratory findings:
(1) anemia and leukoerythroblastosis
Pathologic locations of hematopoietic cells:
(1) interstitial infiltrates
(2) within the alveolar airspace and/or alveolar wall
(3) within vascular lumina and/or vascular walls (especially subintimal) and/or perivascular infiltrates
(4) peribronchial infiltrates
(5) mass-like infiltrate
(6) pleura
The infiltrates of hematopoietic cells may consist of:
(1) megakaryocytes (CD61 positive)
(2) erythroid precursors (hemoglobin positive)
(3) myeloid precursors (myeloperoxidase positive)
Additional pathologic findings may include:
(1) interstitial fibrosis
(2) intra-alveolar hemorrhage
