Wesson and Ling reported the Clinical Opiate Withdrawal Scale (COWS) for patients undergoing opiate withdrawal. The authors are from CNS Medications Development in Oakland and the University of California Los Angeles.
Patient selection: possible opiate withdrawal
Parameters:
(1) resting pulse rate in beats per minute, after sitting or reclining for 1 minute
(2) sweating and/or chills
(3) restlessness
(4) pupil size in room light
(5) bone and/or joint aches
(6) runny nose and/or tearing, not accounted for by cold or allergies
(7) upset
(8) tremor of outstretched hands
(9) yawning
(10) anxiety and/or irritability
(11) gooseflesh
Parameters |
Findings |
Points |
resting pulse rate |
<= 80 |
0 |
|
81 to 100 |
1 |
|
101 to 120 |
2 |
|
> 120 |
4 |
sweating and/or chills |
none |
0 |
|
subjective report |
1 |
|
flushed or observable moisture on face |
2 |
|
beads of sweat on brow or face |
3 |
|
sweat streaming off face |
4 |
restlessness |
able to sit still |
0 |
|
difficulty sitting still but able to |
1 |
|
frequently shifting or extraneous movement of limbs |
3 |
|
unable to sit still for more than a few seconds |
5 |
pupil size |
pinned or normal size for room light |
0 |
|
possibly larger than normal for room light |
1 |
|
moderately dilated |
2 |
|
dilated with only the rim of the iris is visible |
5 |
bone and/or joint aches |
none |
0 |
|
mild, diffuse |
1 |
|
severe diffuse aching |
2 |
|
rubbing joints or muscles; unable to still because of discomfort |
4 |
runny nose and/or tearing |
none |
0 |
|
nasal stuffiness or unusually moist eyes |
1 |
|
nose running or tearing |
2 |
|
nose constantly running or tears streaming down face |
4 |
GI upset |
none |
0 |
|
stomach cramps |
1 |
|
nausea or loose stool |
2 |
|
vomiting or diarrhea |
3 |
|
multiple episodes of diarrhea or vomiting |
5 |
tremor |
none |
0 |
|
felt but not observed |
1 |
|
slight tremor observed |
2 |
|
gross tremor or muscle twitching |
4 |
yawning |
no yawning |
0 |
|
yawns once or twice during assessment |
1 |
|
yawns >= 3 times |
2 |
|
yawns several times per minute |
4 |
anxiety and/or irritability |
none |
0 |
|
increasing irritability or anxiousness |
1 |
|
obviously irritable or anxious |
2 |
|
participation difficult due to anxiety or irritability |
4 |
gooseflesh |
skin is smooth |
0 |
|
piloerection of skin or hairs standing up on arms |
3 |
|
prominent piloerection |
5 |
total COWS score =
= SUM(points for all 11 items)
Interpretation:
• minimum score: 0
• maximum score: 48
• The higher the score the more severe the withdrawal.
Total Score |
Withdrawal |
0 to 4 |
none or minimal |
5 to 12 |
mild |
13 to 24 |
moderate |
25 to 36 |
moderate to severe |
37 to 48 |
severe |
Purpose: To evaluate a patient for opiate withdrawal using the Clinical Opiate Withdrawal Scale (COWS) of Wesson and Ling.
Specialty: Toxicology, Emergency Medicine, Critical Care
Objective: severity, prognosis, stage, selection, failure handling and therapy escalation, response to therapy, compliance/adherence, disease progression
ICD-10: F11,