Pearson et al reported a clinical severity rating scheme for patients with sickle cell disease. This was developed at the Children's Hospital and Research Center in Oakland, California.
Patient selection: pediatric patients with sickle cell disease
Interval: past year
Events are classifed from least (1) to most (5) severe.
Non-Infectious
Event |
Severity |
acute chest syndrome requiring transfusion |
5 |
acute chest syndrome not requiring transfusion |
4 |
aplastic epidose |
5 |
splenic sequestration |
5 |
stroke |
5 |
surgery for a potentially life-threatening complication |
5 |
minor surgery requiring general anesthesia |
4 |
minor surgery requiring local anesthesia |
3 |
any complication requiring chronic transfusion |
5 |
unremitting priapism |
4 |
remitting priapism |
3 |
major psychiatric diagnosis requiring medical treatment |
4 |
seizure |
4 |
pain |
3 |
pain treated at home |
1 |
secondary illness requiring medical treatment |
3 |
Infection
Event |
Severity |
meningitis |
5 |
sepsis |
5 |
osteomyelitis |
4 |
pneumonia |
4 |
pyelonephritis |
4 |
fever requiring hospitalization |
3 |
fever treated as an outpatient |
2 |
urinary tract infection |
3 |
otitis media |
2 |
Specialty: Hematology Oncology, Clinical Laboratory, Genetics