Rabeneck et al proposed a simple clinical staging system for patients with HIV infection which predicted the risk of progression to AIDS over a 3 year period.
Parameters:
(1) CD4 lymphocyte count
(2) history or presence of thrush
(3) history or presence of night sweats
|
Parameter |
Finding |
Points |
|
CD4 lymphocyte count |
> 500 per µL |
0 |
|
|
200 - 500 per µL |
1 |
|
|
< 200 per µL |
2 |
|
history or presence of thrush |
absent |
0 |
|
|
present |
1 |
|
history or presence of night sweats |
absent |
0 |
|
|
present |
1 |
clinical score =
= SUM(points for the 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
|
Clinical Score |
Stage |
Proportion of Patients Progressing to AIDS over a 3 Year Period |
|
0 |
I |
15% |
|
1 or 2 |
II |
29% |
|
3 or 4 |
III |
55% |
Limitations:
• This staging scheme was reported in 1993, before the wide availability of newer treatment modalities. In patients being treated with newer agents, the rate of progression is much less.
Specialty: Infectious Diseases
ICD-10: ,
