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Freiburger Comorbidity Index (FCI) for Multiple Myeloma

Purpose: To evluate a patient with multiple myeloma using the Freiburger Comorbidity Index (FCI) of Kleber et al.

Description

Kleber et al reported the use of the Freiberger Comorbidity Index (FCI) in patients with multiple myeloma. This can help to identify a patient who may benefit from more aggressive management. The authors are from the University of Freiburg in Germany.


 

Patient selection: multiple myeloma

 

Parameters:

(1) Karnofsky Performance Status (KPS)

(2) lung disease

(3) estimated GFR by the MDRD equation in mL per min per 1.73 sq meter

Parameter

Finding

Points

Karnofsky Performance Status

> 70%

0

 

<= 70%

1

lung disease

none or mild

0

 

moderate or severe

1

estimated GFR

>= 30

0

 

< 30

1

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 3

• The higher the score the worse the overall survival.

 

Total Score

Median Overall Survival

0

118 months (10 years)

1

53 months

2 or 3

25 months

 


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Objective

ICD-10