Computerized Risk Scoring System of Gallo et al for Heparin-Induced Thrombocytopenia Risk (HIT-CR)

Description

Gallo et al reported a simple score for assessing the risk of heparin-induced thrombocytopenia in a patient. This is based on 2 of the 4 parameters used in the HIT score. The authors are from the University of Arizona and University Medical Center Phoenix.

Patient selection: being treated with heparin

Parameters:

(1) thrombocytopenia

(2) timing of platelet count fall (based on number of days after starting heparin)

The reference point for the platelet count was the maximum platelet count during the time interval (1) starting 24 hours before starting heparin and (2) stopping at the time scoring performed.

Parameter	Finding	Points
thrombocytopenia	decrease > 50% AND nadir >= 20,000 per µL	2
	decrease 30-50% OR nadir 10,000-19,999 per µL	1
	decrease < 30% OR nadir < 10,000 per µL	0
timing of platelet fall	within 1 day	1
	2 to 4 days	0
	5 to 10 days	2
	10 to 20 days	1
	> 20 days	0

where:

• What constitutes the nadir is not defined. One interpretation is that the nadir is the lowest platelet count. Another interpretation it is the difference between baseline and minimum count (i.e., delta platelet count at the nadir). The latter makes more sense.

total score =

= SUM(points for both parameters)

Interpretation:

• minimum score: 0

• maximum score: 4

• A score >= 3 had a sensitivity of 0.88 and specificity of 0.84.

To read more or access our algorithms and calculators, please log in or register.

Computerized Risk Scoring System of Gallo et al for Heparin-Induced Thrombocytopenia Risk (HIT-CR)

Description

Specialty