Le Deley et al used conversion factors for comparing doses of alkylating agents in patients undergoing chemotherapy for solid tumors. The authors are from the Societe Francaise d'Oncologie Pediatrique.
Reference drug: cyclophosphamide
Reference dose: 1 gram per square meter BSA
Alkylating Agent
Dose Equivalent to 1 gram per square meter cyclophosphamide
busulfan
100 mg per square meter
carmustine
100 mg per square meter
dacarbazine
500 mg per square meter
ifosfamide
4 g per square meter
lomustine
100 mg per square meter
mechlorethamine
12 mg per square meter
melphalan
23.35 mg per square meter
procarbazine
1 g per square meter
thiotepa
150 mg per square meter
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