Wildman et al developed an score to measure the physiologic derangement associated with an acute exacerbation of COPD and/or asthma. The authors are from Northern General Hospital Sheffield, Intensive Care National Audit & Research Centre London, and the London School of Hygiene and Tropical Medicine.
Patient selection: exacerbation of an obstructive airways disease (COPD, asthma, both)
Parameters:
(1) heart rate in beats per minute
(2) mean arterial pressure (MAP) in mm Hg
(3) arterial pH
(4) serum sodium in mmol/L
(5) blood urea in mmol/L
(6) serum creatinine in µmol/L
(7) serum albumin in g/L
(8) white blood cell count in 10^9/L
Parameter |
Finding |
Points |
---|---|---|
heart rate |
< 80 |
3 |
|
80 to 109 |
0 |
|
110 to 129 |
2 |
|
130 to 149 |
3 |
|
150 to 169 |
5 |
|
>= 170 |
7 |
MAP |
< 40 |
19 |
|
40 to 49 |
12 |
|
50 to 59 |
9 |
|
60 to 69 |
6 |
|
70 to 89 |
3 |
|
90 to 99 |
0 |
|
>= 100 |
4 |
pH |
< 7.00 |
9 |
|
7.00 to 7.09 |
6 |
|
7.10 to 7.19 |
3 |
|
7.20 to 7.24 |
1 |
|
>= 7.25 |
0 |
serum sodium |
< 130 |
6 |
|
130 to 134 |
2 |
|
135 to 144 |
0 |
|
>= 145 |
2 |
blood urea |
< 2.5 |
0 |
|
2.5 to 6.7 |
8 |
|
6.8 to 11.9 |
16 |
|
12 to 17.9 |
22 |
|
>= 18.0 |
24 |
serum creatinine |
< 150 |
0 |
|
150 to 199 |
5 |
|
>= 200 |
8 |
serum albumin |
< 15 |
20 |
|
15 to 19.9 |
14 |
|
20 to 24.9 |
8 |
|
25 to 29.9 |
6 |
|
30 to 34.9 |
4 |
|
>= 35 |
0 |
WBC count |
< 4 |
7 |
|
4 to 14.9 |
0 |
|
15 to 19.9 |
1 |
|
20 to 24.9 |
4 |
|
>= 25 |
7 |
total CAPS =
= SUM(points for all 8 parameters)
Interpretation:
• minimum score: 0
• maximum score: 100
• The higher the score the worse the overall survival.
X =
= (0.07530 * (score)) - 3.367
probability of mortality =
= 1 / (1 + EXP((-1) * X))
Purpose: To evaluate a patient with an exacerbation of COPD or asthma using the COPD and Asthma Physiology Score (CAPS) of Wildman et al.
Specialty: Pulmonology
Objective: severity, prognosis, stage, disease progression
ICD-10: J40, J41, J42, J43, J44, J45, J47,