Patient selection: adult female from 45 to 80 years of age
Parameters:
(1) age in years
(2) ethnicity
(3) pack years of smoking
(4) number of alcoholic drinks per day
(5) body mass index (BMI)
(6) years of education
(7) regular use of NSAIDS
(8) family history of colon cancer
(9) regular use of multivitamins
(10) ever used estrogens
(11) diabetes
|
Parameters
|
Finding
|
Points
|
|
ethnicity
|
white
|
2.6
|
|
|
Latino
|
0
|
|
|
black
|
17.7
|
|
|
Hawaiian
|
7
|
|
|
Japanese
|
18.1
|
|
NSAID use
|
yes
|
0
|
|
|
not currently
|
8.7
|
|
|
no
|
10.1
|
|
family history
|
no
|
0
|
|
|
yes
|
14.5
|
|
multivitamins
|
yes
|
0
|
|
|
no
|
8
|
|
diabetes
|
no
|
0
|
|
|
yes
|
11.5
|
|
estrogens
|
yes currently
|
0
|
|
|
previously
|
9
|
|
|
no
|
10.9
|
points for age over range from 45 to 80 years =
= (-0.038405 * ((age)^2)) + (7.6291 * (age)) - 265.4
points for BMI over range from 20 to 35 kg per square meter =
= (0.024 * ((BMI)^2)) - (0.64 * (BMI)) + 3.2
points for years of education over range from 8 to 14 =
= (-0.3442 * ((years)^2)) + (9.2971 * (years)) - 52.449
points for years of education from 14 to 16 years =
= 35.507 - (1.8116 * (years))
points for pack years of smoking over range from 0 to 10 =
= (0.85507 * (years))
points for pack years of smoking over range from 10 to 50 =
= (-0.00062112 * ((years)^2)) + (0.1503 * (years)) + 7.1304
points for alcoholic drinks per day over range from 0 to 10=
= (0.033644 * ((drinks)^2)) + (2.7174 * (drinks)) - 0.49689
|
Overages
|
Use
|
|
BMI over 35
|
10.1
|
|
BMI under 20
|
0
|
|
drinks over 10
|
29.7
|
|
education less than 8
|
0
|
|
education over 16 years
|
6.5
|
|
pack years over 50
|
13.0
|
total score =
= SUM(points for all 11 parameters)
Interpretation:
• minimum score: 0
• maximum score: 238
|
Total Score
|
10 year risk of colorectal cancer in percent
|
|
0 to 233
|
10^((0.0096811*(score))-0.92997)
|
|
> 233
|
> 20%
|
