Patient selection: adult male from 45 to 80 years of age
Parameters:
(1) age in years
(2) ethnicity
(3) pack years of smoking
(4) number of alcoholic drinks per day
(5) body mass index (BMI)
(6) years of education
(7) regular use of aspirin
(8) family history of colon cancer
(9) regular use of multivitamins
(10) ounces of red meat eaten per day
(11) diabetes
(12) hours of moderate physical activity per day
|
Parameters
|
Finding
|
Points
|
|
ethnicity
|
white
|
0
|
|
|
Latino
|
1.5
|
|
|
black
|
6.7
|
|
|
Hawaiian
|
13.5
|
|
|
Japanese
|
17.6
|
|
aspirin
|
yes
|
0
|
|
|
not currently
|
7.3
|
|
|
no
|
8.8
|
|
family history
|
no
|
0
|
|
|
yes
|
10.2
|
|
multivitamins
|
yes
|
0
|
|
|
no
|
8.8
|
|
diabetes
|
no
|
0
|
|
|
yes
|
4.4
|
points for age over range from 45 to 80 years =
= (-0.02936*((age)^2)) + (6.5059 * (age)) - 233.26
points for moderate physical activity per day over range from 0 to 2 hours =
= (0.586 * ((hours)^2)) - (3.9589 * (hours)) + 5.5718
points for BMI over range from 20 to 35 kg per square meter =
= (0.03079 * ((BMI)^2)) - (0.69941 * (BMI)) + 1.5469
points for years of education over range from 8 to 12 =
= (-0.21994 * ((years)^2)) + (6.5982 * (years)) - 38.71
points for years of education from 14 to 16 years =
= 29.4 - (1.45 * (years))
points for pack years of smoking over range from 0 to 50 =
= (0.0035 * ((years)^2)) + (0.086 * (years)) - 0.27
points for alcoholic drinks per day over range from 0 to 2=
= (6.085 * (drinks))
points for alcoholic drinks per day over range from 2 to 12=
= (0.73313 * (drinks)) + 10.447
points for red meat over range from 0 to 2 ounces per day =
= (2.7859 * (ounces)) - 0.0953
points for red meat over range from 2 to 4 ounces per day =
= (0.58651 * (ounces)) + 4.3988
|
Overages
|
Use
|
|
physical activity > 2 hours
|
0
|
|
BMI over 35
|
14.7
|
|
BMI under 20
|
0
|
|
drinks over 12
|
19.4
|
|
red meat over 4 ounces
|
6.7
|
|
education over 16 years
|
6.2
|
|
pack years over 50
|
12.6
|
total score =
= SUM(points for all 12 parameters)
Interpretation:
• minimum score: 0
• maximum score: 210
|
Total Score
|
10 year risk of colorectal cancer in percent
|
|
0 to 188
|
10^((0.010583*(score))-0.79253)
|
|
> 188
|
> 15%
|
