Patient selection: acute myeloid leukemia
Criteria for unfitness to receive nonintensive chemotherapy - one or more of the following:
(1) refractory congestive heart failure
(2) pulmonary disease with DLco <= 65% or FEV1<= 65% of predicted
(3) dyspnea at rest
(4) need for supplemental oxygen
(5) pleural neoplasm or uncontrolled lung neoplasm
(6) acute viral hepatitis
(7) cirrhosis at Child B or C
(8) active infection resistant to anti-infective therapy
(9) current mential illness requiring psychiatric hospitalization, institutionalization or intensive outpatient care
(10) cognitive impairment with dependence not controlled by the caregiver
(11) uncontrolled neoplasia