The World Health Organization (WHO) recommends blood transfusion only in pediatric patients with malaria who demonstrate anemia. The goal is to be frugal in the use of blood without jeopardizing the patient's health..
Patient: pediatric patient with malaria and anemia
Parameters:
(1) hemoglobin in g/dL (after resuscitation)
(2) respiratory distress (including deep and labored breathing)
(3) level of malaria transmission
Hemoglobin in g/dL |
Respiratory Distress |
Malaria Transmission |
Transfuse? |
<= 4 g/dL |
NA |
NA |
Yes |
4 - 5 g/dL |
Yes |
endemic |
Yes |
4 - 7 g/dL |
Yes |
non-endemic |
Yes |
where:
• A seriously ill patient who is dehydrated should be rehydrated prior to evaluation for transfusion.
• On page 143 of the WHO guidelines, the hemoglobin range for moderate to severe anemia is 4-5 g/dL while on page 191 it is 4-6 g/dL.
Additional reasons to consider transfusions in a patient with moderate to severe anemia (page 143):
(1) impaired consciousness
(2) shock
(3) heart failure
(4) high level parasitemia (> 10% of RBCs parasitized)
Transfusion is not recommended if the patient does not meet any of the above criteria.
All patients should receive effective anti-malarial therapy.
Specialty: Infectious Diseases