Description

Such et al stratified the risk in chronic myelomonocytic leukemia (CMML) based on cytogenetic findings. The authros are from multiple institutions in Spain.


Patient selection: chronic myelomonocytic leukemia (CMML)

 

Cytogenetic Result

Risk Level

normal karyotype

low

loss of Y chromosome

low

trisomy 8

high

monosomy chromosome 7 or del(7q)

high

complex karyotype (>=3 abnormalities)

high

any other pattern

intermediate

 

 

Risk Level

5-Year Survival

low

35%

intermediate

26%

high

4%

 


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