Liu et al reported the DAPT score for evaluating a patient who has had an acute cerebral infarction (ACI). This can help to identify a patient who may benefit from dual antiplatelet therapy (clopidogrel plus aspirin). The authors are from Nongxia Medical University and Gansu Provincial Hospital in China.
Patient selection: acute cerebral infarct, age 18 to 89 years, non-TIA
Parameters:
(1) age in years
(2) hypertension
(3) hyperhomocysteinemia
(4) percent ipsilateral carotid artery stenosis
Parameter
Finding
Points
age
< 50 years
0
>= 50 years
1
hypertension
no
0
Grade 1
1
Grade 2
2
Grade 3
3
hyperhomocysteinemia
no
0
yes
1
ipsilateral carotid stenosis
none
0
< 50%
0
>= 50%
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• A score >= 3 indicates that the patient may benefit from aspirin plus clopidogrel.
Performance:
• The area under the ROC curve is 0.78.
• The sensitivity at the cutoff is 63% with specificity 91%.
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