Kiewiet et al reported a decision rule for a patient with secondary abdominal sepsis following initial surgery. This can help to identify a patient with ongoing infection. The authors are from the Academic Medical Centre in Amsterdam.
Patient selection: secondary peritonitis following initial surgical management
Parameters:
(1) contamination
(2) defecation
(3) inotropic medications
(4) body temperature in °C
(5) heart rate in beats per minute
(6) hemoglobin in mmol/L (the conversion factor from g/dL to mmol/L appears to be 0.6206).
Parameter |
Finding |
Points |
Beta-Coefficient |
contamination |
local |
0 |
0 |
|
diffuse |
7 |
0.76695 |
defecation |
no |
14 |
1.46956 |
|
yes |
0 |
0 |
inotropic meds |
no |
0 |
0 |
|
yes |
14 |
1.40856 |
body temperature |
< 35.5°C |
9 |
0.91645 |
|
35.5 to 39°C |
0 |
0 |
|
> 39°C |
9 |
0.91645 |
heart rate |
<= 90 bpm |
0 |
0 |
|
> 90 bpm |
6 |
0.67818 |
hemoglobin |
<= 5 mmol/L (8.1 g/dL) |
10 |
1.09552 |
|
> 5 mmol/L |
0 |
0 |
total score =
= SUM(points for all 6 parameters)
X =
= SUM(beta coefficients) - 4.412803 (original)
= SUM(beta coefficients) - 3.135282 (updated)
probability of persistent sepsis =
= 1 / (1 + EXP((-1) * X))
Interpretation:
• minimum score: 0
• maximum score: 60
• The higher the score the greater the risk of ongoing peritonitis.
Total Score |
Risk Group |
Abdominal Sepsis |
0 to 20 |
low |
11% |
21 to 40 |
intermediate |
35% |
> 40 |
high |
67% |
Risk Group |
Perform CT |
Repeat Decision Rule |
low |
no |
24 hours |
intermediate |
consider |
12 hours |
high |
yes |
12 hours if CT negative |
Performance:
• The area under the ROC curve is 0.80.
Specialty: Infectious Diseases