Sonis et al used a modification of the dental disturbance classification and severity rating scale developed by Dahllof et al to evaluate children who have received chemotherapy and cranial radiation therapy for acute lymphoblastic leukemia. This can help determine the severity of the dental complications and the need for clinical intervention. The authors are from the Harvard School of Dental Medicine, Dana Farber Cancer Institute and New England Medical Center Floating Hospital.
Teeth excluded from the analysis because of a high frequency of abnormalities in the general population:
(1) maxillary lateral incisors
(2) third molars
(3) second premolars (agenesis)
Since there is a maximum of 32 teeth, the maximal number of teeth that can be assessed is 22 (4 third molars + 4 second premolars + 2 maxillary lateral incisors = 10)
Dental Component |
Description |
Classification Type |
Severity Rating |
root |
normal |
I |
0 |
|
arrest with short, tapered V-shaped roots (more than 50% of normal root length) |
II |
1 |
|
anomalies in root number |
IV |
1 |
|
arrest with shortened, blunted roots (less than 50% of normal root development) |
III |
3 |
|
total arrest of root development |
V |
5 |
crown |
normal |
VI |
0 |
|
enamel hypoplasia (notches on proximal surfaces) |
VII |
2 |
whole |
microdontia |
VIII |
4 |
|
agenesis |
IX |
6 |
Based on the data shown in Table 2 (page 2647):
(1) more than one abnormality may be present, except with agenesis
(2) type II and III should not be present in the same tooth
(3) a type I tooth should not have a root abnormality
(4) a type VI tooth should not also be classified as type VII
mean disturbance severity rating =
= (CUMULATIVE SUM((number of teeth showing dental change) * (points for the severity rating))) / (number of teeth evaluated)
The most severe mean disturbance severity ratings were seen in children < 5 years of age who received >= 2,400 cGy of cranial radiation.
There are 2 ways to implement this rating system:
(1) A columnar input with a row for each potential tooth, with exclusions coded in.
(2) A simple listing of each classification item with the number of teeth showing those findings.
The second method is implemented because it is simpler, while the first would be more accurate.
Specialty: Hematology Oncology, Otolaryngology
ICD-10: ,