The prevalence of diarrhea and with vomiting in patients with acute gastroenteritis can help distinguish between different pathogens during an outbreak.
diarrhea-to-vomiting ratio = D/V ratio =
= (percentage of patients with diarrhea) / (percentage of patients with vomiting)
where:
• Some patients will have both diarrhea and vomiting.
Interpretation (Dalton et al, page 12):
• A ratio >= 2.5 suggests an ETEC (enterotoxigenic E. coli) outbreak. This reflects that diarrhea is more common than vomiting. The range (1.3 to 45.5) had a median of 7.1
• A ratio < 2.5 suggests a viral gastroenteritis. The range (0.6 to 5.5) had a median of 1.4.
• Patients with ETEC and a ratio < 2.5 had a median duration of illness > 60 hours (Dalton et al, page 14).
Using the data ranges:
Ratio |
Interpretation |
< 1.3 |
viral |
1.3 to 2.49 |
probably viral |
2.5 to 5.5 |
probably ETEC |
> 5.5 |
ETEC |
Performance:
• A cutoff >= 2.5 has a sensitivity of 82% and specificity of 92%.
Limitations:
• The interpretation may be misleading if the number of affected patients is low or if the total number of people with diarrhea and/or vomiting is low.
Purpose: To determine the diarrhea-to-vomiting ratio (D/V ratio) during an outbreak of acute gastroenteritis.
Specialty: Infectious Diseases, Surgery, general, Gastroenterology
Objective: clinical diagnosis, including family history for genetics, other testing
ICD-10: A02.0, A08, A09, J10.8, J11.8, K52, K59.1,