Heroin (diacetyl morphine) comes in different types which can have significant clinical implications.
Types of heroin:
(1) based on color, consistency and manufacture
(2) based on purity (based on base concentration and inert additives)
(3) based on noninert additives
Color and Consistency
Production
Features
black (to dark brown) tar
crude extract
lower potency; requires heat for water solubility; can contain pathogenic bacteria
brown
partially purified (base)
burns at lower temperature so can be smoked; poor water solubility until treated with acid
"white" (white, off-white, pink, light brown)
highly purified (diacetyl morphine HCl), acidic
burns at a higher temperature; highly soluble in water; often used IV
Purity depends on production and "cutting" with inert additives. A change in supply with higher potency can increase deaths.
Noninert additives:
(1) fentanyl (increases high, increases addictive potential, increases risk of death)
(2) strychnine (acts as stimulant)
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Specialty: Toxicology, Emergency Medicine, Critical Care