Description

The distinction between acute bacterial and acute viral meningitis can be difficult. A model based on analysis of 500 cases of community acquired meningitis identified 4 independent variables which could be analyzed to give the probability of acute bacterial meningitis.


 

Four variables:

(1) CSF PMN count (CSF WBC count times percent PMNs in CSF differential)

(2) CSF protein

(3) blood glucose

(4) WBC count

 

probability of acute bacterial meningitis =

= 1 / (1 + (EXP (-L)))

 

L =

= (CSF PMN count factor) + (CSF protein factor) + (blood glucose factor) + (WBC count factor) - 11

 

CSF PMN count factor =

= 0.003213 * (CSF PMN count in 10^6 per liter)

 

CSF protein factor =

= 2.365 * (CSF protein in g/L)

 

blood glucose factor =

= 0.6143 * (blood glucose in mmol/L)

 

WBC count factor =

= 0.02086 * (WBC count in 10^9 per liter)

 


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