Description

DeZern and Guinan listed the differential diagnosis for pancytopenia in young adults.


Infection:

(1) Epstein-Barr virus (EBV)

(2) cytomegalovirus (CMV)

(3) human herpesvirus 6 (HHV6)

(4) hepatitis B

(5) hepatitis C

(6) HIV

(7) parvovirus

 

Toxic:

(1) recreational drugs

(2) prescription drugs

(3) toxin exposure

 

Bone marrow failure:

(1) dyskeratosis congenita (DKC)

(2) Fanconi's anemia (FA)

(3) Shwachman-Diamond syndrome

(4) Diamond-Blackfan anemia

(5) anorexia nervosa

 

Pregnancy

 

Clonal disorders:

(1) leukemia

(2) paroxysmal nocturnal hemoglobinuria (PNH)

(3) histiocytic disorders


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