The number of conditions associated with noncaseating granulomas is large.
Infection:
(1) mycobacterial disease (tuberculosis, atypical, leprosy)
(2) spirochetal diseases (yaws, syphilis)
(3) deep and opportunistic fungal infection
(4) cat-scratch disease
(5) Q fever
(6) Whipple's disease
(7) leishmaniasis
(8) toxoplasmosis
(9) schistosomiasis
(10) brucellosis
(11) yersiniosis
(12) LGV
Chemical or foreign body exposure
(1) berylliosis
(2) zirconium
(3) foreign body reaction
(4) silica
(6) talc
(7) cocaine
Malignancy:
(1) carcinomatosis (malignancy sarcoidosis syndrome)
(2) malignant lymphoma (Hodgkin's, non-Hodgkin's)
(3) pulmonary lymphangioleiomyomatosis
Immune dysfunction:
(1) Churg Strauss syndrome
(2) giant cell arteritis
(3) common variable immunodeficiency
(4) primary biliary cirrhosis
(5) hypersensitivity pneumonitis
(6) Crohn's disease
(7) sarcoidosis
(8) Wegener's granulomatosis
(9) polyarteritis nodosa
(10) SLE
(11) orofacial granulomatosis
(12) Blau's syndrome
Other:
(1) dialysis
(2) drug reaction
(3) Histiocytosis X or Langerhans granulomatosis
(4) chronic granulomatous disease (leukocyte oxidase defect)
(5) lipogranulomatosis
