Capecitabine (tradename Xeloda, Roche) is fluoropyrimidine carbonate that is converted to 5-FU in vivo. It is used in the chemotherapy of colon and breast cancers. It can be dosed based on the patient's body surface area.
The standard dose is 1,250 mg per square meter body surface area. This is divided into 2 doses, one taken in the morning and the second in the evening.
BSA in square meters
Total Daily Dose in mg
BID Dose in mg
<=1.25
3,000 mg
1,500 mg
1.26 - 1.37
3,300 mg
1,650 mg
1.38 - 1.51
3,600 mg
1,800 mg
1.52 - 1.65
4,000 mg
2,000 mg
1.66 - 1.77
4,300 mg
2,150 mg
1.78 - 1.91
4,600 mg
2,300 mg
1.92 - 2.05
5,000 mg
2,500 mg
2.06 - 2.17
5,300 mg
2,650 mg
>= 2.18
5,600 mg
2,800 ng
BSA
BID Dose in mg
Number of 500 mg Tablets per Dose
Number of 150 mg Tablets per Dose
<=1.25
1,500 mg
3
0
1.26 - 1.37
1,650 mg
3
1
1.38 - 1.51
1,800 mg
3
2
1.52 - 1.65
2,000 mg
4
0
1.66 - 1.77
2,150 mg
4
1
1.78 - 1.91
2,300 mg
4
2
1.92 - 2.05
2,500 mg
5
0
2.06 - 2.17
2,650 mg
5
1
>= 2.18
2,800 ng
5
2
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