Description

Inada and Inagaki reported dose equivalence for drugs used to treat Parkinson's disease in Japan. The authors are from Seiwa Hospital and Aoyama Gakuin University in Japan.


Drug

Equivalent Dose

amantadine

100

benztropine

1

biperiden

2

diphenhydramine

30

hydroxyzine

65

mazaticol

8

metixene

10

piroheptine

4

profenamine

100

promethazine

50

trihexyphenidyl

4

 

where:

• Benztropine and Metixene are no longer available in Japan.

 

multiple of the equivalent dose =

= (actual dose) / (equivalent dose)

 

To convert to another drug in the table:

 

dose for new drug =

= (multiple of the equivalent dose for previous drug) * (equivalent dose for new drug)


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