Drug Induced Liver Disease | Medical Algorithm

The R-ratio can help to classify the type of drug-induced liver injury (DILI) that a patient is experiencing.

Patient selection: drug-induced liver injury (DILI)

Parameters:

(1) serum ALT

(2) upper limit of normal for serum ALT

(3) serum alkaline phosphatase

(4) upper limit of normal for serum alkaline phosphatase

R-ratio =

= ((serum ALT) / (ULN ALT)) / ((serum alkaline phosphatase) / (ULN alkaline phosphatase))

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R-Ratio in Drug-Induced Liver Injury (DILI)