Drugs are a leading cause of reversible cognitive decline. Review of medications is an important step in the evaluation of a patient who presents with unexplained cognitive impairment.
Medications which can cause cognitive impairment:
(1) aminophylline
(2) amiodarone
(3) antibiotics
(4) anticholinergic agents
(5) antihistamines
(6) antineoplastic agents
(7) barbiturates
(8) benzodiazepines or other sedative-hypnotic agents
(9) bromides
(10) bromocriptine
(11) cimetidine
(12) clonidine
(13) corticosteroids
(14) cytokine immunotherapy
(15) digoxin
(16) disulfiram
(17) diuretics (directly or through an effect on electrolytes)