A person with diabetes mellitus may be a candidate for pancreas transplant if certain criteria are present.
Type of Transplant |
Creatinine Clearance |
pancreas transplant alone (PTA) |
usually > 60 mL/min; may be given in 40-60 mL/min range |
sequential pancreas after kidney transplant (PAKT) |
usually > 40 mL/min |
pancreas and kidney transplant, simultaneous (SKPT) |
usually < 30 mL/min |
Diabetes status criteria
(1) presence of insulin-dependent diabetes mellitus
(2) presence of 2 or more diabetic complications (proliferative retinopathy, diabetic nephropathy, peripheral or autonomic neuropathy, microangiopathy, accelerated atherosclerosis, difficult glucose control with frequent ketoacidosis and/or hypoglycemia)
General health status criteria:
(1) sufficient cardiopulmonary function
(2) able to undergo surgery
(3) able to withstand immunosuppression
(4) absence of any organ failures other than renal failure
Patient status criteria:
(1) emotionally and psychologically suitable
(2) sufficient social support and economic resources
(3) compliant with long term drug regimens
Specialty: Gastroenterology, Surgery, general